A synthetic peptide for use as a blocking control in assays to test for specificity of CDH3 antibody, Alternative Names: CDH3 control peptide, CDH3 antibody Blocking Peptide, Anti-CDH3 Blocking Peptide, Cadherin 3 Type 1 Blocking Peptide, P-Cadherin Blocking Peptide, CDHP Blocking Peptide, HJMD Blocking Peptide, PCAD Blocking Peptide
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
P-Cadherin (CDH3)
背景
CDH3 is a classical cadherin from the cadherin superfamily. The protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Its gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in its gene have been associated with congential hypotrichosis with juvenile macular dystrophy.