A synthetic peptide for use as a blocking control in assays to test for specificity of EGLN2 antibody, Alternative Names: EGLN2 control peptide, EGLN2 antibody Blocking Peptide, Anti-EGLN2 Blocking Peptide, egl nine homolog 2, C. elegans Blocking Peptide, DKFZp434E026 Blocking Peptide, EIT6 Blocking Peptide, HIFPH1 Blocking Peptide, HPH-3 Blocking Peptide, PHD1 Blocking Peptide, EGLN2, EGLN-2, EGLN 2, EGLN-2 Blocking Peptide, EGLN 2 Blocking Peptide
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
PHD1 (EGLN2)
(Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))
背景
The hypoxia inducible factor (HIF) is a transcriptional complex which is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. EGLN2 encodes an enzyme responsible for this posttranslational modification. Alternative splicing of EGLN2 results in three transcript variants encoding different isoforms. The hypoxia inducible factor (HIF) is a transcriptional complex which is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation.