A synthetic peptide for use as a blocking control in assays to test for specificity of DTNB antibody, Alternative Names: DTNB control peptide, DTNB antibody Blocking Peptide, Anti-DTNB Blocking Peptide, Dystrobrevin Beta Blocking Peptide, MGC17163 Blocking Peptide, MGC57126 Blocking Peptide
DTNB is dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin.