Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) Peptide
PCMT1
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
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- 抗原 See all PCMT1 products
- PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))
- 蛋白类型
- Synthetic
- 宿主
- 哺乳动物
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- APYDAIHVGA AAPVVPQALI DQLKPGGRLI LPVGPAGGNQ MLEQYDKLQD
- 产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of PCMT1 antibody,
Alternative Names: PCMT1 control peptide, PCMT1 antibody Blocking Peptide, Anti-PCMT1 Blocking Peptide, Protein-L-Isoaspartate Blocking Peptide, D-Aspartate O-Methyltransferase Blocking Peptide, PCMT1, PCMT-1, PCMT 1, PCMT-1 Blocking Peptide, PCMT 1 Blocking Peptide
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- 应用备注
- Optimal conditions should be determined by the investigator
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- 缓冲液
- PBS
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C long term.
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- 抗原
- PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))
- 背景
- Three classes of protein carboxyl methyltransferases, distinguished by their methyl-acceptor substrate specificity, have been found in prokaryotic and eukaryotic cells. The type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the free carboxyl groups of D-aspartyl and L-isoaspartyl residues. These methyl-accepting residues result from the spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues and represent sites of covalent damage to aging proteins PCMT1 (EC 2.1.1.77) is a protein repair enzyme that initiates the conversion of abnormal D-aspartyl and L-isoaspartyl residues to the normal L-aspartyl form.
- 分子量
- 25 kDa
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