Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) Peptide
PCMT1
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
产品编号 ABIN936828
发货至:
中国
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Contact Info
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Quick Overview for Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) Peptide (ABIN936828)
抗原
PCMT1
(Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))
宿主
哺乳动物
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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蛋白类型
- Synthetic
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序列
- APYDAIHVGA AAPVVPQALI DQLKPGGRLI LPVGPAGGNQ MLEQYDKLQD
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of PCMT1 antibody,
Alternative Names: PCMT1 control peptide, PCMT1 antibody Blocking Peptide, Anti-PCMT1 Blocking Peptide, Protein-L-Isoaspartate Blocking Peptide, D-Aspartate O-Methyltransferase Blocking Peptide, PCMT1, PCMT-1, PCMT 1, PCMT-1 Blocking Peptide, PCMT 1 Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))
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背景
- Three classes of protein carboxyl methyltransferases, distinguished by their methyl-acceptor substrate specificity, have been found in prokaryotic and eukaryotic cells. The type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the free carboxyl groups of D-aspartyl and L-isoaspartyl residues. These methyl-accepting residues result from the spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues and represent sites of covalent damage to aging proteins PCMT1 (EC 2.1.1.77) is a protein repair enzyme that initiates the conversion of abnormal D-aspartyl and L-isoaspartyl residues to the normal L-aspartyl form.
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分子量
- 25 kDa
抗原
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