RE1-Silencing Transcription Factor (REST) Peptide
REST
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
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- 抗原 See all REST products
- REST (RE1-Silencing Transcription Factor (REST))
- 蛋白类型
- Synthetic
- 宿主
- 哺乳动物
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- ANMGMALTND MYDLHELSKA ELAAPQLIML ANVALTGEAS GSCCDYLVGE
- 产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of Rest antibody,
Alternative Names: Rest control peptide, Rest antibody Blocking Peptide, Anti-Rest Blocking Peptide, RE1-silencing transcription factor Blocking Peptide, 2610008J04Rik Blocking Peptide, AA407358 Blocking Peptide, MGC150099 Blocking Peptide, NRSF Blocking Peptide
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- 应用备注
- Optimal conditions should be determined by the investigator
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- 缓冲液
- PBS
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C long term.
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- 抗原
- REST (RE1-Silencing Transcription Factor (REST))
- 背景
- Rest is a transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Rest restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Rest mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.
- 分子量
- 118 kDa
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