Glucokinase (Hexokinase 4) (GCK) Peptide
GCK
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
Quick Overview for Glucokinase (Hexokinase 4) (GCK) Peptide (ABIN936387)
抗原
GCK
(Glucokinase (Hexokinase 4) (GCK))
宿主
哺乳动物
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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蛋白类型
- Synthetic
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序列
- RVMLVKVGEG EEGQWSVKTK HQMYSIPEDA MTGTAEMLFD YISECISDFL
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of GCK antibody,
Alternative Names: GCK control peptide, GCK antibody Blocking Peptide, Anti-GCK Blocking Peptide, glucokinase, hexokinase 4 Blocking Peptide, FGQTL3 Blocking Peptide, GK Blocking Peptide, GLK Blocking Peptide, HHF3 Blocking Peptide, HK4 Blocking Peptide, HKIV Blocking Peptide, HXKP Blocking Peptide, MODY2 Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- GCK (Glucokinase (Hexokinase 4) (GCK))
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背景
- Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI).
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分子量
- 51 kDa
抗原
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