Insulin-Degrading Enzyme (IDE) Peptide
IDE
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
产品编号 ABIN936344
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Quick Overview for Insulin-Degrading Enzyme (IDE) Peptide (ABIN936344)
抗原
IDE
(Insulin-Degrading Enzyme (IDE))
宿主
哺乳动物
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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蛋白类型
- Synthetic
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序列
- LDVHIGSLSD PPNIAGLSHF CEHMLFLGTK KYPKENEYSQ FLSEHAGSSN
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of IDE antibody,
Alternative Names: IDE control peptide, IDE antibody Blocking Peptide, Anti-IDE Blocking Peptide, insulin-degrading enzyme Blocking Peptide, FLJ35968 Blocking Peptide, INSULYSIN Blocking Peptide -
纯化方法
- Immunoaffinity chromatography
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- IDE (Insulin-Degrading Enzyme (IDE))
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背景
- This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion.
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分子量
- 118 kDa
抗原
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