Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2) Peptide
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Quick Overview for Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2) Peptide (ABIN936245)
抗原
宿主
资源
应用范围
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蛋白类型
- Synthetic
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序列
- YTRYQQYGAE ECVLQMGGVL CPRPGCGAGL LPEQGQRKVT CEGGNGLGCG
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of Park2 antibody,
Alternative Names: Park2 control peptide, Park2 antibody Blocking Peptide, Anti-Park2 Blocking Peptide, Parkinson disease, autosomal recessive, juvenile 2, parkin Blocking Peptide, MGC130518 Blocking Peptide, PRKN Blocking Peptide, Park2, Park-2, Park 2, Park-2 Blocking Peptide, Park 2 Blocking Peptide -
纯化方法
- Serum
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- Parkin (PARK2) (Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))
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背景
- Park2 functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. These substrates include SYT11, CCNE1, GPR37, STUB1, a 22 kDa O-linked glycosylated isoform of SNCAIP, SEPT5 and AIMP2. Park2 may play a more general role in the ubiquitin proteasomal pathway by participating in the removal and/or detoxification of abnormally folded or damaged protein. Park2 limits the production of reactive oxygen species (ROS).
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分子量
- 51 kDa
抗原
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