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Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) Peptide

SDHB 适用: 哺乳动物 宿主: 合成 BP, WB, IHC
产品编号 ABIN936209
发货至: 中国
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Quick Overview for Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) Peptide (ABIN936209)

抗原

SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))

宿主

哺乳动物

资源

  • 6
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • 蛋白类型

    Synthetic

    序列

    YRWMIDSRDD FTEERLAKLQ DPFSLYRCHT IMNCTRTCPK GLNPGKAIAE

    产品特性

    A synthetic peptide for use as a blocking control in assays to test for specificity of SDHB antibody,
    Alternative Names: SDHB control peptide, SDHB antibody Blocking Peptide, Anti-SDHB Blocking Peptide, Succinate Dehydrogenase Complex Subunit B Iron Sulfur Blocking Peptide, IP Blocking Peptide, PGL4 Blocking Peptide, SDH Blocking Peptide, SDH1 Blocking Peptide, SDHIP Blocking Peptide
  • 应用备注

    Optimal conditions should be determined by the investigator

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C long term.
  • 抗原

    SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))

    背景

    Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.

    分子量

    31 kDa
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