Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) Peptide
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Quick Overview for Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) Peptide (ABIN936209)
抗原
宿主
资源
应用范围
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蛋白类型
- Synthetic
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序列
- YRWMIDSRDD FTEERLAKLQ DPFSLYRCHT IMNCTRTCPK GLNPGKAIAE
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of SDHB antibody,
Alternative Names: SDHB control peptide, SDHB antibody Blocking Peptide, Anti-SDHB Blocking Peptide, Succinate Dehydrogenase Complex Subunit B Iron Sulfur Blocking Peptide, IP Blocking Peptide, PGL4 Blocking Peptide, SDH Blocking Peptide, SDH1 Blocking Peptide, SDHIP Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))
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背景
- Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
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分子量
- 31 kDa
抗原
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