Retinoic Acid Receptor, alpha (RARA) Peptide
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北京 101111
Quick Overview for Retinoic Acid Receptor, alpha (RARA) Peptide (ABIN936051)
抗原
宿主
资源
应用范围
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蛋白类型
- Synthetic
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序列
- YESVEVGGPT PNPFLVVDFY NQNRACLLPE KGLPAPGPYS TPLRTPLWNG
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of RARA antibody,
Alternative Names: RARA control peptide, RARA antibody Blocking Peptide, Anti-RARA Blocking Peptide, Retinoic Acid Receptor Alpha Blocking Peptide, NR1B1 Blocking Peptide, RAR Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))
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背景
- Retinoid signaling is transduced by 2 families of nuclear receptors, retinoic acid receptor (RAR) and retinoid X receptor, which form RXR/RAR heterodimers. In the absence of ligand, DNA-bound RXR/RARA represses transcription by recruiting the corepressors NCOR1, SMRT, and histone deacetylase. When ligand binds to the complex, it induces a conformational change allowing the recruitment of coactivators, histone acetyltransferases, and the basic transcription machinery.
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分子量
- 51 kDa
抗原
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