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Minichromosome Maintenance Complex Component 3 (MCM3) Peptide

MCM3 适用: 哺乳动物 宿主: 合成 BP, WB, IHC
产品编号 ABIN936013
发货至: 中国

Quick Overview for Minichromosome Maintenance Complex Component 3 (MCM3) Peptide (ABIN936013)

抗原

MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

宿主

哺乳动物

资源

  • 5
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • 蛋白类型

    Synthetic

    序列

    YAYFKKVLEK EKKRKKRSED ESETEDEEEK SQEDQEQKRK RRKTRQPDAK

    产品特性

    A synthetic peptide for use as a blocking control in assays to test for specificity of MCM3 antibody,
    Alternative Names: MCM3 control peptide, MCM3 antibody Blocking Peptide, Anti-MCM3 Blocking Peptide, Minichromosome Maintenance Complex Component 3 Blocking Peptide, HCC5 Blocking Peptide, MGC1157 Blocking Peptide, P1-MCM3 Blocking Peptide, P1.h Blocking Peptide, RLFB Blocking Peptide, MCM3, MCM-3, MCM 3, MCM-3 Blocking Peptide, MCM 3 Blocking Peptide

    纯化方法

    The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
  • 应用备注

    Optimal conditions should be determined by the investigator

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C long term.
  • 抗原

    MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

    背景

    MCM3 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.

    分子量

    91 kDa
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