Insulin Induced Gene 1 (INSIG1) Peptide
INSIG1
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
Quick Overview for Insulin Induced Gene 1 (INSIG1) Peptide (ABIN935998)
抗原
INSIG1
(Insulin Induced Gene 1 (INSIG1))
宿主
哺乳动物
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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蛋白类型
- Synthetic
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序列
- WWVPPCCGTA SAVIGLLYPC IDRHLGEPHK FKREWSSVMR CVAVFVGINH
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of INSIG1 antibody,
Alternative Names: INSIG1 control peptide, INSIG1 antibody Blocking Peptide, Anti-INSIG1 Blocking Peptide, Insulin Induced Gene 1 Blocking Peptide, MGC26273 Blocking Peptide, INSIG1, INSIG-1, INSIG 1, INSIG-1 Blocking Peptide, INSIG 1 Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- INSIG1 (Insulin Induced Gene 1 (INSIG1))
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背景
- Oxysterols regulate cholesterol homeostasis through the liver X receptor (LXR)- and sterol regulatory element-binding protein (SREBP)-mediated signaling pathways. This gene is an insulin-induced gene. INSIG1 is an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. INSIG1 binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins.
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分子量
- 25 kDa
抗原
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