Vasodilator-Stimulated phosphoprotein (VASP) Peptide
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Quick Overview for Vasodilator-Stimulated phosphoprotein (VASP) Peptide (ABIN935974)
抗原
宿主
资源
应用范围
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蛋白类型
- Synthetic
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序列
- WSVPNGPSPE EVEQQKRQQP GPSEHIERRV SNAGGPPAPP AGGPPPPPGP
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of VASP antibody,
Alternative Names: VASP control peptide, VASP antibody Blocking Peptide, Anti-VASP Blocking Peptide, vasodilator-stimulated phosphoprotein Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- VASP (Vasodilator-Stimulated phosphoprotein (VASP))
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背景
- Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
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分子量
- 42 kDa
抗原
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