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- 抗原
- Anti-Trypsin
- 蛋白类型
- Recombinant
- 蛋白结构域
- AA 25-418
- 宿主
- 人
- 资源
- 大肠杆菌（E. Coli）
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MEDPQGDAAQ KTDTSHHDQD HPTFNKITPN LAEFAFSLYR QLAHQSNSTN IFFSPVSIAT AFAMLSLGTK ADTHDEILEG LNFNLTEIPE AQIHEGFQEL LRTLNQPDSQ LQLTTGNGLF LSEGLKLVDK FLEDVKKLYH SEAFTVNFGD TEEAKKQIND YVEKGTQGKI VDLVKELDRD TVFALVNYIF FKGKWERPFE VKDTEEEDFH VDQVTTVKVP MMKRLGMFNI QHCKKLSSWV LLMKYLGNAT AIFFLPDEGK LQHLENELTH DIITKFLENE DRRSASLHLP KLSITGTYDL KSVLGQLGIT KVFSNGADLS GVTEEAPLKL SKAVHKAVLT IDEKGTEAAG AMFLEAIPMS IPPEVKFNKP FVFLMIDQNT KSPLFMGKVV NPTQK
- 产品特性
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Purified recombinant Human Antitrypsin protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher. - 纯度
- > 90 % pure
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- 应用备注
- Antitrypsin protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Supplied as a liquid in 20 mM Tris, pH 7.5, containing 10 % glycerol, 0 mM DTT, and 0 mM EDTA.
- 储存液
- Dithiothreitol (DTT)
- 注意事项
- This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- RT/-20 °C
- 储存方法
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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- 抗原
- Anti-Trypsin
- 物质类
- Antibody
- 背景
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Alpha 1 proteinase inhibitor (Antitrypsin) has a characteristic secondary structure of beta sheets and alpha helices. That is a serum glycoprotein synthesized in the liver. It acts as an elastase inhibitor, primarily inhibiting neutrophil elastase, chymotrypsin, collagenase, leucocytic proteases, plasmin, and thrombin, which may be released during inflammatory reactions in the lung. Also an increase in Antitrypsin occurs as an acute phase response to tissue necrosis and inflammation. Serum level of Antitrypsin is elevated in rheumatoid arthritis, bacterial infections, vasculitis, and carcinomatosis. Recombinant Antitrypsin protein was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: Serpin A1 protein, Clade A member 1 protein, Alpha-1 antiproteinase protein, serum trypsin inhibitor, Alpha 1 protease inhibitor protein, Protease inhibitor 1 protein, A1AT protein, Alpha-1 Antitrypsin protein, A1A protein, Alpha 1 antitrypsin protein, Serpin peptidase inhibitor clade A member 1 protein, MGC9222 protein, PRO2275 protein, MGC23330 protein, cysteine proteinase inhibitor protein, SerpinA1 protein, MGC23330 protein, A1AT protein, AAT protein, Antitrypsin protein, PI protein, Serine proteinase inhibitor protein, Alpha 1 antiproteinase protein, alpha1 PI protein, alpha 1 AT protein, PI1 protein, SERP1NA1 protein, alpha1 proteinase inhibitor protein - 分子量
- 44.4 kDa (395 AA)
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