Purified recombinant Hepatitis C Virus NS3 protein Expression System: E.coli
纯化方法
Proprietary chromatographic technique
纯度
> 90 % pure
应用备注
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
缓冲液
20 mM Tris-HCl, pH 8.0, with 20 mM beta mercaptoethanol.
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
4 °C/-20 °C
储存方法
Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
抗原
HCV NS3
(Hepatitis C Virus NS3 (HCV NS3))
物质类
Viral Protein
背景
HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6). Alternative Names: HCV NS3 protein, HCV protein, Hep C protein, Hepatitis C protein, HCV Recombinant protein, HCV NS3 Genotype-1a protein, HCV NS3 Genotype 1a protein