Vacuolar-sorting Protein SNF8 (SNF8) (Middle Region) Peptide
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Quick Overview for Vacuolar-sorting Protein SNF8 (SNF8) (Middle Region) Peptide (ABIN8115656)
抗原
宿主
资源
应用范围
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蛋白结构域
- Middle Region
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原理
- SNF8 Peptide - middle region
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序列
- DHTVVLQLAE KNGYVTVSEI KASLKWETER ARQVLEHLLK EGLAWLDLQA
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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This is a synthetic peptide designed for use in combination with anti-SNF8 Antibody(ARP57950_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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缓冲液
- Lyophilized powder
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))
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背景
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Background Information: ELL encodes an RNA polymerase II transcription factor that undergoes frequent translocation in acute myeloid leukemia (AML). In addition to its elongation activity, ELL contains a novel type of RNA polymerase II interaction domain that is capable of repressing polymerase activity in promoter-specific transcription. EAP30 is a subunit of the ELL complex. EAP30 can interact with ELL and derepress ELL's inhibitory activity in vitro.SNF8, VPS25 (MIM 610907), and VPS36 (MIM 610903) form ESCRT-II (endosomal sorting complex required for transport II), a complex involved in endocytosis of ubiquitinated membrane proteins. SNF8, VPS25, and VPS36 are also associated in a multiprotein complex with RNA polymerase II elongation factor.
Alternative Symbols: Dot3, EAP30, VPS22
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分子量
- 29kDa
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基因ID
- 11267
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NCBI登录号
- NP_009172
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UniProt
- Q96H20
抗原
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