Uracil-DNA Glycosylase (UNG) (N-Term) Peptide
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Quick Overview for Uracil-DNA Glycosylase (UNG) (N-Term) Peptide (ABIN8115517)
抗原
宿主
资源
应用范围
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蛋白结构域
- N-Term
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原理
- UNG Peptide - N-terminal region
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序列
- LYSFFSPSPA RKRHAPSPEP AVQGTGVAGV PEESGDAAAI PAKKAPAGQE
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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This is a synthetic peptide designed for use in combination with anti- UNG Antibody (ARP88038_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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缓冲液
- Lyophilized powder
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- UNG (Uracil-DNA Glycosylase (UNG))
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背景
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Background Information: This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases.
Alternative Symbols: DGU, UDG, UNG1, UNG2, HIGM4, HIGM5, UNG15
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分子量
- 35 kDa
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基因ID
- 7374
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NCBI登录号
- NP_003353
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UniProt
- P13051
抗原
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