Unc-13 Homolog B (UNC13B) (Middle Region) Peptide
UNC13B
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN8115449
发货至:
中国
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Contact Info
Our Local Distributor
中国
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北京 101111
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Quick Overview for Unc-13 Homolog B (UNC13B) (Middle Region) Peptide (ABIN8115449)
抗原
UNC13B
(Unc-13 Homolog B (UNC13B))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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原理
- UNC13B Peptide - middle region
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序列
- SYDLDYPERR AISPTSSSRY GSSCNVSQGS SQLSELDQYH EQDDDHRETD
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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缓冲液
- Lyophilized powder
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- UNC13B (Unc-13 Homolog B (UNC13B))
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背景
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Background Information: This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.
Alternative Symbols: UNC13, MUNC13, Unc13h2
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分子量
- 181 kDa
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基因ID
- 10497
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NCBI登录号
- NP_006368
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UniProt
- O14795
抗原
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