Transmembrane Emp24-Like Trafficking Protein 10 (TMED10) (Middle Region) Peptide
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Quick Overview for Transmembrane Emp24-Like Trafficking Protein 10 (TMED10) (Middle Region) Peptide (ABIN8114398)
抗原
资源
应用范围
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蛋白结构域
- Middle Region
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原理
- TMED10 Peptide - middle region
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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This is a synthetic peptide designed for use in combination with anti-TMED10 antibody ( ARP58728_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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缓冲液
- Lyophilized powder
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- TMED10 (Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))
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背景
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Background Information: TMED10 is involved in vesicular protein trafficking.This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
Alternative Symbols: P24(DELTA), S31I125, S31III125, TMP21, Tmp-21-I, p23
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分子量
- 24kDa
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基因ID
- 10972
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NCBI登录号
- NP_006818
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UniProt
- P49755
抗原
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