SPC25, NDC80 Kinetochore Complex Component, Homolog (SPC25) (C-Term) Peptide
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Quick Overview for SPC25, NDC80 Kinetochore Complex Component, Homolog (SPC25) (C-Term) Peptide (ABIN8112563)
抗原
宿主
资源
应用范围
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蛋白结构域
- C-Term
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原理
- SPC25 Peptide - C-terminal region
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序列
- PYMFSMSINE AKEYEVYDSS PHLECLAEFQ EKVRKTNNFS AFLANIRKAF
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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This is a synthetic peptide designed for use in combination with anti- SPC25 Antibody (ARP90654_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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缓冲液
- Lyophilized powder
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- SPC25 (SPC25, NDC80 Kinetochore Complex Component, Homolog (SPC25))
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背景
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Background Information: This gene encodes a component of the kinetochore-associated NDC80 protein complex, which is required for the mitotic spindle checkpoint and for microtubule-kinetochore attachment. During meiosis in mouse, the protein localizes to the germinal vesicle and then is associated with the chromosomes following germinal vesicle breakdown. Knockdown of this gene in oocytes results in precocious polar body extrusion, chromosome misalignment and aberrant spindle formation. Alternative splicing results in multiple transcript variants.
Alternative Symbols: Spbc25, 2600017H08Rik, 2610205L13Rik
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分子量
- 19 kDa
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基因ID
- 66442
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NCBI登录号
- NP_001186052
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UniProt
- Q3UA16
抗原
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