Sequestosome 1 (SQSTM1) (Middle Region) Peptide
Our Local Distributor
北京 101111
Quick Overview for Sequestosome 1 (SQSTM1) (Middle Region) Peptide (ABIN8111330)
抗原
宿主
资源
应用范围
-
-
蛋白结构域
- Middle Region
-
原理
- SQSTM1 Peptide - middle region
-
序列
- RKIALESEGR PEEQMESDNC SGGDDDWTHL SSKEVDPSTG ELQSLQMPES
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
This is a synthetic peptide designed for use in combination with anti- SQSTM1 Antibody (ARP97313_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
缓冲液
- Lyophilized powder
-
储存条件
- -20 °C
-
储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
-
-
- SQSTM1 (Sequestosome 1 (SQSTM1))
-
背景
-
Background Information: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
Alternative Symbols: p60, p62, A170, OSIL, PDB3, ZIP3, p62B, FTDALS3
-
分子量
- 39 kDa
-
基因ID
- 8878
-
NCBI登录号
- NP_001135770
-
UniProt
- Q13501
抗原
-
