Scavenger Receptor Class B, Member 2 (SCARB2) (Middle Region) Peptide
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Quick Overview for Scavenger Receptor Class B, Member 2 (SCARB2) (Middle Region) Peptide (ABIN8111165)
抗原
宿主
资源
应用范围
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蛋白结构域
- Middle Region
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原理
- SCARB2 Peptide - middle region
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序列
- EEILRGETPR VEEVGPYTYR ELRNKANIQF GDNGTTISAV SNKAYVFERD
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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This is a synthetic peptide designed for use in combination with anti- SCARB2 Antibody (ARP84414_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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缓冲液
- Lyophilized powder
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))
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背景
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Background Information: The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alternative Symbols: AMRF, EPM4, LGP85, CD36L2, HLGP85, LIMP-2, LIMPII, SR-BII
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分子量
- 52 kDa
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基因ID
- 950
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NCBI登录号
- NP_001191184
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UniProt
- Q14108
抗原
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