rho GTPase Activating Protein 26 (ARHGAP26) (Middle Region) Peptide
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Quick Overview for rho GTPase Activating Protein 26 (ARHGAP26) (Middle Region) Peptide (ABIN8110496)
抗原
宿主
资源
应用范围
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蛋白结构域
- Middle Region
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原理
- ARHGAP26 Peptide - middle region
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序列
- LWMEAMDGRE PVYNSNKDSQ SEGTAQLDSI GFSIIRKCIH AVETRGINEQ
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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This is a synthetic peptide designed for use in combination with anti-RHG26 Antibody (ARP73910_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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缓冲液
- Lyophilized powder
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- GRAF (ARHGAP26) (rho GTPase Activating Protein 26 (ARHGAP26))
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背景
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Background Information: Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene.
Alternative Symbols: GRAF, GRAF1, OPHN1L, OPHN1L1
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分子量
- 89kDa
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基因ID
- 23092
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NCBI登录号
- NP_055886
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UniProt
- Q9UNA1
抗原
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