Renalase, FAD-Dependent Amine Oxidase (RNLS) (Middle Region) Peptide
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Quick Overview for Renalase, FAD-Dependent Amine Oxidase (RNLS) (Middle Region) Peptide (ABIN8110277)
抗原
宿主
资源
应用范围
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蛋白结构域
- Middle Region
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原理
- Rnls Peptide - middle region
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序列
- GMKIGVPWSC RYLSSHPCIC FISIDNKKRN IESSECGPSV VIQTTVPFGV
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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This is a synthetic peptide designed for use in combination with anti-Rnls Antibody (ARP59612_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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缓冲液
- Lyophilized powder
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))
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背景
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Background Information: Rnls is a probable FAD-dependent amine oxidase secreted by the kidney, which circulates in blood and modulates cardiac function and systemic blood pressure. It degrades catecholamines such as dopamine, norepinephrine and epinephrine in vitro. It lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.
Alternative Symbols: 6530404N21Rik, AI452315, AW060440, C10orf59
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分子量
- 33kDa
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基因ID
- 67795
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NCBI登录号
- NP_001161290
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UniProt
- A7RDN6
抗原
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