Pyrin and HIN Domain Family, Member 1 (PYHIN1) Peptide
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Quick Overview for Pyrin and HIN Domain Family, Member 1 (PYHIN1) Peptide (ABIN8109719)
抗原
资源
应用范围
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原理
- PYHIN1 Peptide
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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This is a synthetic peptide designed for use in combination with anti-PYHIN1 antibody ( ARP50875_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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缓冲液
- Lyophilized powder
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))
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背景
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Background Information: PYHIN1 belongs to the HIN-200 family. This protein is major mediator of the tumor suppressor activity of IFN in breast cancer cells. It promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization, and HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells.
Alternative Symbols: IFIX, MGC23885, RP11-520H16.1
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分子量
- 55kDa
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基因ID
- 149628
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NCBI登录号
- NP_689714
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UniProt
- Q6K0P9
抗原
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