Paired-Like Homeobox 2b (PHOX2B) (C-Term) Peptide
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Quick Overview for Paired-Like Homeobox 2b (PHOX2B) (C-Term) Peptide (ABIN8107576)
抗原
宿主
资源
应用范围
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蛋白结构域
- C-Term
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原理
- PHOX2B Peptide - C-terminal region
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序列
- RAAAAAAAAA KNGSSGKKSD SSRDDESKEA KSTDPDSTGG PGPNPNPTPS
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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This is a synthetic peptide designed for use in combination with anti-PHX2B Antibody (ARP74127_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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缓冲液
- Lyophilized powder
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- PHOX2B (Paired-Like Homeobox 2b (PHOX2B))
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背景
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Background Information: The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome.
Alternative Symbols: CCHS, PMX2B, NBLST2, NBPhox
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分子量
- 34kDa
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基因ID
- 8929
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NCBI登录号
- NP_003915
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UniProt
- Q99453
抗原
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