Minichromosome Maintenance Deficient 8 (MCM8) Peptide
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Quick Overview for Minichromosome Maintenance Deficient 8 (MCM8) Peptide (ABIN8105451)
抗原
资源
应用范围
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原理
- MCM8 Peptide
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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This is a synthetic peptide designed for use in combination with anti-MCM8 antibody ( ARP36668_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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缓冲液
- Lyophilized powder
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))
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背景
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Background Information: MCM8 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described.The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Alternative Symbols: C20orf154, MGC119522, MGC119523, MGC12866, MGC4816, REC, dJ967N21.5
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分子量
- 94kDa
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基因ID
- 84515
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NCBI登录号
- NP_115874
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UniProt
- Q9UJA3
抗原
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