IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) (N-Term) Peptide
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Quick Overview for IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) (N-Term) Peptide (ABIN8102981)
抗原
宿主
资源
应用范围
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蛋白结构域
- N-Term
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原理
- IMPDH2 Peptide - N-terminal region
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序列
- MADYLISGGT SYVPDDGLTA QQLFNCGDGL TYNDFLILPG YIDFTADQVD
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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This is a synthetic peptide designed for use in combination with anti-IMPDH2 Antibody(ARP54365_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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缓冲液
- Lyophilized powder
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- IMPDH2 (IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))
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背景
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Background Information: IMPDH2 is the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. It catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. IMPDH2 is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
Alternative Symbols: IMPD2, IMPDH-II
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分子量
- 56kDa
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基因ID
- 3615
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NCBI登录号
- NP_000875
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UniProt
- P12268
抗原
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