Immunoglobulin Superfamily, Member 8 (IGSF8) (Middle Region) Peptide
Our Local Distributor
北京 101111
Quick Overview for Immunoglobulin Superfamily, Member 8 (IGSF8) (Middle Region) Peptide (ABIN8102973)
抗原
宿主
资源
应用范围
-
-
蛋白结构域
- Middle Region
-
原理
- IGSF8 Peptide - middle region
-
序列
- LAVEAGAPYA ERLAAGELRL GKEGTDRYRM VVGGAQAGDA GTYHCTAAEW
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
This is a synthetic peptide designed for use in combination with anti-IGSF8 Antibody (ARP59875_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
缓冲液
- Lyophilized powder
-
储存条件
- -20 °C
-
储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
-
-
- IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))
-
背景
-
Background Information: IGSF8 may play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. IGSF8 may regulate proliferation and differentiation of keratinocytes. IGSF8 may be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. IGSF8 may also play a role on integrin-dependent morphology and motility functions. IGSF8 may participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.
Alternative Symbols: CD316, CD81P3, EWI2, PGRL, EWI-2, KCT-4, LIR-D1
-
分子量
- 65kDa
-
基因ID
- 93185
-
NCBI登录号
- NP_443100
-
UniProt
- Q969P0
抗原
-
