Histone Deacetylase 3 (HDAC3) (C-Term) Peptide
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Quick Overview for Histone Deacetylase 3 (HDAC3) (C-Term) Peptide (ABIN8102599)
抗原
宿主
资源
应用范围
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蛋白结构域
- C-Term
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原理
- HDAC3 Peptide - C-terminal region
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序列
- VQIHDVPADL LTYDRTDEAD AEERGPEENY SRPEAPNEFY DGDHDNDKES
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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This is a synthetic peptide designed for use in combination with anti- HDAC3 Antibody (ARP80651_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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缓冲液
- Lyophilized powder
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- HDAC3 (Histone Deacetylase 3 (HDAC3))
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背景
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Background Information: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
Alternative Symbols: HD3, RPD3, RPD3-2
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分子量
- 49 kDa
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基因ID
- 8841
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NCBI登录号
- NP_003874
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UniProt
- O15379
抗原
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