Hexokinase 1 (HK1) (Middle Region) Peptide
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Quick Overview for Hexokinase 1 (HK1) (Middle Region) Peptide (ABIN8102481)
抗原
宿主
资源
应用范围
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蛋白结构域
- Middle Region
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原理
- HK1 Peptide - middle region
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序列
- DCVSVQHVCT IVSFRSANLV AATLGAILNR LRDNKGTPRL RTTVGVDGSL
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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This is a synthetic peptide designed for use in combination with anti- HK1 Antibody (ARP80866_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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缓冲液
- Lyophilized powder
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- Hexokinase 1 (HK1)
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背景
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Background Information: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus, the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein.
Alternative Symbols: HKD, HKI, HXK1, HMSNR, HK1-ta, HK1-tb, HK1-tc
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分子量
- 100 kDa
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基因ID
- 3098
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NCBI登录号
- NP_000179
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UniProt
- P19367
抗原
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