Hepatocyte Nuclear Factor 4, alpha (HNF4A) (N-Term) Peptide
Our Local Distributor
北京 101111
Quick Overview for Hepatocyte Nuclear Factor 4, alpha (HNF4A) (N-Term) Peptide (ABIN8102400)
抗原
宿主
资源
应用范围
-
-
蛋白结构域
- N-Term
-
原理
- HNF4A Peptide - N-terminal region
-
序列
- MRLSKTLVDM DMADYSAALD PAYTTLEFEN VQVLTMGNDT SPSEGTNLNA
-
-
Hepatocyte Nuclear Factor 4, alpha (HNF4A) peptide
HNF4A 适用: 人, Pig, 犬 宿主: 合成 BP, Imm
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
This is a synthetic peptide designed for use in combination with anti-HNF4A Antibody (ARP31946_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
缓冲液
- Lyophilized powder
-
储存条件
- -20 °C
-
储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
-
-
- HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))
-
背景
-
Background Information: The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms.
Alternative Symbols: HNF4, HNF4a7, HNF4a8, HNF4a9, HNF4alpha, MODY, MODY1, NR2A1, NR2A21, TCF, TCF14
-
分子量
- 53kDa
-
基因ID
- 3172
-
NCBI登录号
- NP_000448
-
UniProt
- P41235
抗原
-
