GTP Cyclohydrolase 1 (GCH1) (N-Term) Peptide
GCH1
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN8102001
发货至:
中国
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Contact Info
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中国
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Quick Overview for GTP Cyclohydrolase 1 (GCH1) (N-Term) Peptide (ABIN8102001)
抗原
GCH1
(GTP Cyclohydrolase 1 (GCH1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- N-Term
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原理
- GCH1 Peptide - N-terminal region
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序列
- PPRPEAKSAQ PADGWKGERP RSEEDNELNL PNLAAAYSSI LSSLGENPQR
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GTP Cyclohydrolase 1 (GCH1) peptide
GCH1 适用: 人, 小鼠, 大鼠 宿主: 合成 BP, Imm
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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This is a synthetic peptide designed for use in combination with anti-GCH1 Antibody (ARP59619_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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缓冲液
- Lyophilized powder
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- GCH1 (GTP Cyclohydrolase 1 (GCH1))
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背景
- This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described, however, not all variants give rise to a functional enzyme.
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分子量
- 27kDa
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基因ID
- 2643
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UniProt
- P30793
抗原
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