GM2 Ganglioside Activator (GM2A) (N-Term) Peptide
Our Local Distributor
北京 101111
Quick Overview for GM2 Ganglioside Activator (GM2A) (N-Term) Peptide (ABIN8101820)
抗原
宿主
资源
应用范围
-
-
蛋白结构域
- N-Term
-
原理
- GM2A Peptide - N-terminal region
-
序列
- SWDNCDEGKD PAVIRSLTLE PDPIIVPGNV TLSVMGSTSV PLSSPLKVDL
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
This is a synthetic peptide designed for use in combination with anti-GM2A Antibody(ARP46007_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
缓冲液
- Lyophilized powder
-
储存条件
- -20 °C
-
储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
-
-
- GM2A (GM2 Ganglioside Activator (GM2A))
-
背景
-
Background Information: This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.
Alternative Symbols: SAP-3, GM2-AP
-
分子量
- 18kDa
-
基因ID
- 2760
-
NCBI登录号
- NP_000396
-
UniProt
- P17900
抗原
-
