gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) Peptide
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Quick Overview for gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) Peptide (ABIN8101260)
抗原
资源
应用范围
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原理
- GABRA1 Peptide
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gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) peptide
GABRA1 宿主: 合成 BP, WB, IHC
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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This is a synthetic peptide designed for use in combination with anti-GABRA1 antibody ( ARP34977_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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缓冲液
- Lyophilized powder
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- GABRA1 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))
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背景
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Targeted Subunit: alpha-1
Background Information: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene.
Alternative Symbols: ECA4, EJM, EJM5
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分子量
- 52kDa
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基因ID
- 2554
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NCBI登录号
- NP_000797
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UniProt
- P14867
抗原
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