Endonuclease G (ENDOG) (Middle Region) Peptide
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Quick Overview for Endonuclease G (ENDOG) (Middle Region) Peptide (ABIN8099600)
抗原
资源
应用范围
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蛋白结构域
- Middle Region
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原理
- ENDOG Peptide - middle region
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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This is a synthetic peptide designed for use in combination with anti-ENDOG antibody ( ARP52054_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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缓冲液
- Lyophilized powder
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- Endonuclease G (ENDOG)
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背景
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Background Information: ENDOG cleaves DNA at double-stranded (DG)n.(DC)n and at single-stranded (DC)n tracts. In addition to deoxyribonuclease activities, ENDOG also has ribonuclease (RNase) and RNase H activities. ENDOG is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA.The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA.
Alternative Symbols: FLJ27463
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分子量
- 28kDa
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基因ID
- 2021
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NCBI登录号
- NP_004426
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UniProt
- Q14249
抗原
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