Crossover junction endonuclease EME1 (EME1) (Middle Region) Peptide
Our Local Distributor
北京 101111
Quick Overview for Crossover junction endonuclease EME1 (EME1) (Middle Region) Peptide (ABIN8098023)
抗原
资源
应用范围
-
-
蛋白结构域
- Middle Region
-
原理
- EME1 Peptide - middle region
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
This is a synthetic peptide designed for use in combination with anti-EME1 antibody ( ARP52988_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
缓冲液
- Lyophilized powder
-
储存条件
- -20 °C
-
储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
-
-
- Crossover junction endonuclease EME1 (EME1)
-
背景
-
Background Information: EME1 interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. EME1 may be required in mitosis for the processing of stalled or collapsed replication forks.EME1 and MUS81 (MIM 606591) form an endonuclease complex that cleaves branched DNA structures, especially those arising during stalled DNA replication (Abraham et al., 2003 [PubMed 14609959]).[supplied by OMIM].
Alternative Symbols: FLJ31364, MMS4L, SLX2A
-
分子量
- 63kDa
-
基因ID
- 146956
-
NCBI登录号
- NP_689676
-
UniProt
- Q96AY2
抗原
-
