Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7) Peptide
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Quick Overview for Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7) Peptide (ABIN8096961)
抗原
资源
应用范围
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原理
- CHRNA7 Peptide
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Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7) peptide
CHRNA7 宿主: 合成 BP, WB, IHC
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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This is a synthetic peptide designed for use in combination with anti-CHRNA7 antibody ( ARP35418_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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缓冲液
- Lyophilized powder
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- CHRNA7 (Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7))
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背景
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Targeted Subunit: alpha-7
Background Information: The protein encoded by CHRNA7 displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin. Once this receptor binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. This gene is located in a region identified as a major susceptibility locus for juvenile myoclonic epilepsy and a chromosomal location involved in the genetic transmission of schizophrenia.
Alternative Symbols: NACHRA7, CHRNA7-2
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分子量
- 56kDa
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基因ID
- 1139
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NCBI登录号
- NP_000737
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UniProt
- P36544
抗原
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