CD207 Molecule, Langerin (CD207) (C-Term) Peptide
Our Local Distributor
北京 101111
Quick Overview for CD207 Molecule, Langerin (CD207) (C-Term) Peptide (ABIN8096502)
抗原
宿主
资源
应用范围
-
-
蛋白结构域
- C-Term
-
原理
- CD207 Peptide - C-terminal region
-
序列
- GDWSWVDDTP FNKVQSARFW IPGEPNNAGN NEHCGNIKAP SLQAWNDAPC
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
This is a synthetic peptide designed for use in combination with anti-CD207 Antibody (ARP63502_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
缓冲液
- Lyophilized powder
-
储存条件
- -20 °C
-
储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
-
-
- CD207 (CD207 Molecule, Langerin (CD207))
-
背景
-
Background Information: The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.
Alternative Symbols: CLEC4K
-
分子量
- 36kDa
-
基因ID
- 50489
-
NCBI登录号
- NP_056532
-
UniProt
- Q9UJ71
抗原
-
