Casein Kinase 1, epsilon (CSNK1E) (N-Term) Peptide
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Quick Overview for Casein Kinase 1, epsilon (CSNK1E) (N-Term) Peptide (ABIN8096304)
抗原
资源
应用范围
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蛋白结构域
- N-Term
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原理
- CSNK1E Peptide - N-terminal region
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Casein Kinase 1, epsilon (CSNK1E) peptide
CSNK1E 适用: 人, 小鼠, 大鼠, 犬 宿主: 合成 BP, Imm
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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This is a synthetic peptide designed for use in combination with anti-CSNK1E antibody ( ARP51987_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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缓冲液
- Lyophilized powder
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- CK1 epsilon (CSNK1E) (Casein Kinase 1, epsilon (CSNK1E))
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背景
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Background Information: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. CSNK1E can phosphorylate a large number of proteins. CSNK1E participates in Wnt signaling and is the central component of the circadian clock. It may act as a negative regulator of circadian rhythmicity by phosphorylating PER1 and PER2. CSNK1E inhibits cytokine-induced granuloytic differentiation.The protein encoded by this gene is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene.
Alternative Symbols: HCKIE, MGC10398, CKIepsilon
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分子量
- 47kDa
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基因ID
- 1454
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NCBI登录号
- NP_001885
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UniProt
- P49674
抗原
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