Bruton Agammaglobulinemia tyrosine Kinase (BTK) (N-Term) Peptide
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Quick Overview for Bruton Agammaglobulinemia tyrosine Kinase (BTK) (N-Term) Peptide (ABIN8095736)
抗原
宿主
资源
应用范围
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蛋白结构域
- N-Term
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原理
- BTK Peptide - N-terminal region
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序列
- LTVHKLSYYE YDFERGRRGS KKGSIDVEKI TCVETVVPEK NPPPERQIPR
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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This is a synthetic peptide designed for use in combination with anti-BTK Antibody (ARP79105_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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缓冲液
- Lyophilized powder
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))
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背景
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Background Information: The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alternative Symbols: AT, ATK, BPK, XLA, IMD1, AGMX1, PSCTK1
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分子量
- 53 kDa
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基因ID
- 695
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NCBI登录号
- NP_000052
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UniProt
- Q5JY90
抗原
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