Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (C-Term) Peptide
Our Local Distributor
北京 101111
Quick Overview for Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (C-Term) Peptide (ABIN8094855)
抗原
资源
应用范围
-
-
蛋白结构域
- C-Term
-
原理
- PDCD8 Peptide - C-terminal region
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
This is a synthetic peptide designed for use in combination with anti-PDCD8 antibody ( ARP40199_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
缓冲液
- Lyophilized powder
-
储存条件
- -20 °C
-
储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
-
-
- AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
-
背景
-
Background Information: AIFM1 (PDCD8) is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, AIFM1 induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9.This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Three alternative transcripts encoding different isoforms have been identified for this gene.
Alternative Symbols: AIF, PDCD8, COXPD6
-
分子量
- 36kDa
-
基因ID
- 9131
-
NCBI登录号
- NP_665812
-
UniProt
- O95831
抗原
-
