Amiloride-Sensitive Cation Channel 3 (ACCN3) (C-Term) Peptide
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Quick Overview for Amiloride-Sensitive Cation Channel 3 (ACCN3) (C-Term) Peptide (ABIN8094504)
抗原
宿主
资源
应用范围
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蛋白结构域
- C-Term
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原理
- ASIC3 Peptide - C-terminal region
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序列
- LCEVFRDKVL GYFWNRQHSQ RHSSTNLLQE GLGSHRTQVP HLSLGPRPPT
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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This is a synthetic peptide designed for use in combination with anti- ACCN3 Antibody (ARP74866_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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缓冲液
- Lyophilized powder
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))
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背景
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Background Information: This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described.
Alternative Symbols: ACCN3, TNaC1, DRASIC, SLNAC1
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分子量
- 59 kDa
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基因ID
- 9311
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NCBI登录号
- NP_004760
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UniProt
- Q9UHC3
抗原
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