Aldo-keto Reductase Family 1 Member C4 (AKR1C4) (N-Term) Peptide
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Quick Overview for Aldo-keto Reductase Family 1 Member C4 (AKR1C4) (N-Term) Peptide (ABIN8094397)
抗原
宿主
资源
应用范围
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蛋白结构域
- N-Term
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原理
- AKR1C4 Peptide - N-terminal region
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序列
- MDPKYQRVEL NDGHFMPVLG FGTYAPPEVP RNRAVEVTKL AIEAGFRHID
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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This is a synthetic peptide designed for use in combination with anti- AKR1C4 Antibody (ARP97778_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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缓冲液
- Lyophilized powder
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))
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背景
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Background Information: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Alternative Symbols: C11, CDR, DD4, CHDR, DD-4, HAKRA, 3-alpha-HSD
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分子量
- 35 kDa
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基因ID
- 1109
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NCBI登录号
- NP_001809
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UniProt
- P17516
抗原
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