Actin, alpha 1, Skeletal Muscle (ACTA1) (N-Term) Peptide
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Quick Overview for Actin, alpha 1, Skeletal Muscle (ACTA1) (N-Term) Peptide (ABIN8093870)
抗原
宿主
资源
应用范围
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蛋白结构域
- N-Term
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原理
- ACTA1 Peptide - N-terminal region
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序列
- GQKDSYVGDE AQSKRGILTL KYPIEHGIIT NWDDMEKIWH HTFYNELRVA
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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This is a synthetic peptide designed for use in combination with anti-ACTA1 Antibody (ARP60969_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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缓冲液
- Lyophilized powder
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))
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背景
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Background Information: The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
Alternative Symbols: ACTA, ASMA, CFTD, CFTD1, CFTDM, MPFD, NEM1, NEM2, NEM3
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分子量
- 42kDa
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基因ID
- 58
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NCBI登录号
- NP_001091
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UniProt
- P68133
抗原
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