Galanin (GAL) Peptide
GAL
宿主: 合成
BP, Func
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- 抗原 See all Galanin (GAL) products
- Galanin (GAL)
- 蛋白类型
- Synthetic
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Functional Studies (Func)
- 原理
- A Selective and Potent Agonist of Galanin 2/3 Receptors
- 序列
- WTLNSAGYLL -NH2
- 特异性
- Toxin target: Galanin 2/3 receptors, Leu10 - C-terminal amidation
- 产品特性
- A Selective and Potent Agonist of Galanin 2/3 Receptors
- 纯度
- ≥98 % (HPLC)
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Galanin (GAL) peptide (Ovalbumin)
GAL 适用: 人 宿主: 合成 Imm, SDS, WB
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- 应用备注
- Antigen Preadsorption Control: 0.1 - 10 nM
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the vial (10,000 x g for 5 minutes) before adding solvent to spin down all the powder to the bottom of the vial. The lyophilized product may be difficult to visualize. Add solvent directly to the centrifuged vial. Gently tap, tilt, and roll the vial to aid dissolution. Avoid vigorous vortexing, light vortexing for up to 3 seconds is acceptable if needed. Soluble in DMSO. Prepare a concentrated stock solution by dissolving the lyophilized peptide in DMSO first (e.g., at a concentration between 100-1000x of the final working concentration). Once the peptide is completely dissolved in DMSO, slowly dilute the solution into the working buffer (or water) to the desired final working concentration. Centrifuge all product preparations before use. Avoid multiple freeze-thaw cycles to maintain biological activity. It is recommended to keep the DMSO concentration as low as possible. For cell assays, a final concentration of 0.1 % -0.5 % DMSO (v/v) is considered safe. For other experiments, a 5 % DMSO (v/v) concentration is recommended.
- 缓冲液
- Lyophilized in 50 % acteonotrile.
- 储存条件
- -20 °C
- 储存方法
- Store the reconstituted solution at -20°C for the shortest time possible. Avoid multiple freeze-thaw cycles. We do not recommend storing the product in working solutions for longer than a day.,Store the reconstituted solution for the shortest time possible at -20°C. We do not recommend storing the product in working solution for longer than one day. Avoid multiple freeze-thaw cycles.
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- 抗原
- Galanin (GAL)
- 背景
- AR-M1896, Gal (2-11) amide,Galanin (2-11) is a neuropeptide that acts as a selective potent galanin 2 and 3 receptor (GalR2/3) agonist. Galanin is a C-terminally amidated 29-residue peptide deriving its name from the N-terminal glycine and C-terminal alanine residue. In humans the peptide contains additional nonamidated serine residue at C terminus. Galanin was firstly isolated from porcine intestine and shown to be widely distributed through the central and peripheral nervous system1-3.Its biological activity includes contraction or relaxation of gut smooth muscles, inhibition of insulin and somatostatin release, and modulation of hormone secretion from the pituitary and adrenal gland. It is believed that galanin plays an important role as a neuromodulator of endocrine secretion and synaptic transmission1.Galanin receptors belong to the family of G-protein coupled receptors and consist of three subtypes: GalR1, GalR2, and GalR3. Additional studies show that galanin and its receptors are involved in the transmission and modulation of nociception2.
- 分子量
- 1136 Da
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