Galanin (GAL) Peptide
GAL
适用: 人
宿主: 合成
BP, Func
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- 抗原 See all Galanin (GAL) products
- Galanin (GAL)
- 蛋白类型
- Synthetic
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Functional Studies (Func)
- 原理
- A Non-Selective and Potent Agonist of Galanin Receptors
- 序列
- GWTLNSAGYL LGPHAVGNHR SFSDKNGLTS -OH
- 特异性
- Toxin target: Galanin receptors
- 产品特性
- A Non-Selective and Potent Agonist of Galanin Receptors
- 纯度
- ≥98 % (HPLC)
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Galanin (GAL) peptide (Ovalbumin)
GAL 适用: 人 宿主: 合成 Imm, SDS, WB
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- 应用备注
- Antigen Preadsorption Control: 1 - 10 nM
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the vial (10,000 x g for 5 minutes) before adding solvent to spin down all the powder to the bottom of the vial. The lyophilized product may be difficult to visualize. Add solvent directly to the centrifuged vial. Gently tap, tilt, and roll the vial to aid dissolution. Avoid vigorous vortexing, light vortexing for up to 3 seconds is acceptable if needed. The product is soluble in pure water at high micromolar concentrations (100 μM - 1 mM). For long-term storage in solution, we recommend preparing a stock solution by dissolving the product in double-distilled water (ddH2O) at a concentration between 100-1000x of the final working concentration. Divide the stock solution into small aliquots and store at -20 °C. Before use, thaw the relevant vial(s) and dilute to the desired working concentration in your working buffer. Centrifuge all product preparations before use. It is recommended to prepare fresh solutions in working buffers just before use. Avoid multiple freeze-thaw cycles to maintain biological activity.
- 缓冲液
- Lyophilized from double distilled water (ddH2O). May contain TFA as a residual counter ion.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods (up to 6 months), small aliquots should be stored at -20°C. We do not recommend storing the product in working solutions for longer than a few days. Avoid multiple freeze-thaw cycles.,The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods (up to 6 months), small aliquots should be stored at -20°C. We do not recommend storing the product in working solutions for longer than a few days. Avoid multiple freeze-thaw cycles.
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- 抗原
- Galanin (GAL)
- 背景
- Galanin is a peptide hormone that acts as a non-selective and potent galanin receptor agonist. In human, Galanin is a C-terminal-amidated 30-residue peptide deriving its name from the N-terminal glycine and C-terminal alanine residue1,2. Galanin receptors belong to the family of G-protein coupled receptors and consist of three subtypes: GalR1, GalR2, and GalR3.Galanin is widely distributed through the central and peripheral nervous system and its biological activity includes contraction or relaxation of gut smooth muscles, inhibition of insulin and somatostatin release, and modulation of hormone secretion from the pituitary and adrenal glands. It is believed that galanin plays an important role as a neuromodulator of endocrine secretion and synaptic transmission1. Additional studies show that galanin and its receptors are involved in the transmission and modulation of nociception of the central nervous system, at spinal cord levels and in the brain2.
- 分子量
- 3157 Da
- UniProt
- P22466
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