Gastrin-Releasing Peptide (GRP) Peptide
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- 抗原 See all Gastrin-Releasing Peptide (GRP) products
- Gastrin-Releasing Peptide (GRP)
- 蛋白类型
- Synthetic
- 宿主
- Bombina bombina (Fire-bellied toad)
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资源
- 合成
- 应用范围
- Blocking Peptide (BP)
- 原理
- A Ligand of the Bombesin G-Protein Coupled Receptor
- 序列
- EQRLGNQWAV GHLM-OH
- 特异性
- Toxin target: Bombesin receptors, Glu1 - Pyrrolidone carboxylic acid
- 产品特性
- A Ligand of the Bombesin G-Protein Coupled Receptor
- 纯度
- ≥98 % (HPLC)
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Gastrin-Releasing Peptide (GRP) peptide (Ovalbumin)
GRP 适用: 人 宿主: 合成 WB, Imm, SDS
Gastrin-Releasing Peptide (GRP) peptide (Ovalbumin)GRP 适用: 大鼠 宿主: 合成 WB, Imm, SDS
Gastrin-Releasing Peptide (GRP) peptide (Ovalbumin)GRP 适用: 小鼠 宿主: 合成 WB, Imm, SDS
Gastrin-Releasing Peptide (GRP) peptide (BSA)GRP 适用: 人 宿主: 合成 WB, Imm, SDS
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- 应用备注
- Antigen Preadsorption Control: 1 - 100 nM
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the vial (10,000 x g for 5 minutes) before adding solvent to spin down all the powder to the bottom of the vial. The lyophilized product may be difficult to visualize. Add solvent directly to the centrifuged vial. Gently tap, tilt, and roll the vial to aid dissolution. Avoid vigorous vortexing, light vortexing for up to 3 seconds is acceptable if needed. The product is soluble in pure water at high micromolar concentrations (100 μM - 1 mM). For long-term storage in solution, we recommend preparing a stock solution by dissolving the product in double-distilled water (ddH2O) at a concentration between 100-1000x of the final working concentration. Divide the stock solution into small aliquots and store at -20 °C. Before use, thaw the relevant vial(s) and dilute to the desired working concentration in your working buffer. Centrifuge all product preparations before use. It is recommended to prepare fresh solutions in working buffers just before use. Avoid multiple freeze-thaw cycles to maintain biological activity.
- 缓冲液
- Lyophilized from double distilled water (ddH2O). May contain TFA as a residual counter ion.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods (up to 6 months), small aliquots should be stored at -20°C. We do not recommend storing the product in working solutions for longer than a few days. Avoid multiple freeze-thaw cycles.,The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods (up to 6 months), small aliquots should be stored at -20°C. We do not recommend storing the product in working solutions for longer than a few days. Avoid multiple freeze-thaw cycles.
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- 抗原
- Gastrin-Releasing Peptide (GRP)
- 背景
- Bombesin is an active neuropeptide originally isolated from amphibian skin but also found in the central and peripheral nervous systems of amphibians1. Later it was established that mammals and birds express two family groups of endogenous Bombesin-like factors, the gastrin-releasing peptides and neuromedin B2. The biological activities of bombesin are mediated through a family of three specific G-protein coupled receptors (GPCRs): BB1 which is also known as a neuromedin B receptor, BB2 also known as a gastrin-releasing peptide receptor and BB3 which is a low affinity binder for the Bombesin-like factors3,4.Bombesin and Bombesin-like factors show a broad range of biological activities such as regulation of smooth muscle contraction, stimulation of neuropeptide and hormone secretion, modulation of neural activity, growth regulation, and mediate anorexic effects in the hypothalamus5.
- 分子量
- 1620.8 Da
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