alpha-conotoxin IMI peptide (Atto 590)
适用: Conus imperialis
宿主: 合成
BP, FM, IF, LCI
产品编号 ABIN7582096
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for alpha-conotoxin IMI peptide (Atto 590) (ABIN7582096)
抗原
alpha-conotoxin IMI
宿主
Conus imperialis
资源
合成
应用范围
Blocking Peptide (BP), Fluorescence Microscopy (FM), Immunofluorescence (IF), Live Cell Imaging (LCI)
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蛋白类型
- Synthetic
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标记
- Atto 590
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原理
- A Potent Antagonist of Mammalian α3/β2 nAChR Conjugated to the Fluorescent Dye ATTO-590
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序列
- GCCSDPRCAW RC-NH2
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特异性
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Toxin target: α3/β2 nAChR,
Disulfide bonds between: Cys2-Cys8, Cys3-Cys12 Cys12 - C-terminal amidation ATTO Fluor-590 -
产品特性
- A Potent Antagonist of Mammalian α3/β2 nAChR Conjugated to the Fluorescent Dye
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alpha-conotoxin IMI peptide
适用: Conus imperialis 宿主: 合成 BP
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应用备注
- Antigen Preadsorption Control: 1 - 2 μM
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge the vial (10,000 x g for 5 minutes) before adding solvent to spin down all the powder to the bottom of the vial. The lyophilized product may be difficult to visualize. Add solvent directly to the centrifuged vial. Gently tap, tilt, and roll the vial to aid dissolution. Avoid vigorous vortexing, light vortexing for up to 3 seconds is acceptable if needed. The product is lyophilized in 0.5 mL conical vial. The product is soluble in pure water to high-micromolar concentrations (5 μM - 1 mM). For long-term storage in solution, we recommend preparing a stock solution by dissolving the product in double distilled water (ddH2O) at a concentration between 100-1000x of the final working concentration. Divide the stock solution into small aliquots and store at -20 °C. Before use, thaw the relevant vial(s) and dilute to the desired working concentration in your working buffer. Centrifuge all product preparations before use. It is recommended to prepare fresh solutions in working buffers just before use. Avoid multiple freeze-thaw cycles to maintain biological activity. Avoid exposure to light.
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缓冲液
- Lyophilized from double distilled water (ddH2O). May contain TFA as a residual counter ion.
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储存条件
- -20 °C
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储存方法
- Store the reconstituted solution at -20°C for the shortest time possible. Avoid multiple freeze-thaw cycles. We do not recommend storing the product in working solutions for longer than a day. Avoid exposure to light.,Store the reconstituted solution at -20°C for the shortest time possible. Avoid multiple freeze-thaw cycles. We do not recommend storing the product in working solutions for longer than a day. Avoid exposure to light.
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- alpha-conotoxin IMI
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背景
- α-CTx ImI, alpha-conotoxin ImI, Alpha-CTx ImI,α-Conotoxin ImI is a 12 amino acid peptidyl toxin isolated from Conus Imperialis venom1, which blocks mammalian neuronal nAChRs located on postsynaptic membranes. This toxin inhibits mammalian neuronal nAChRs (α3/β2 > α7 > α3/β4) in a voltage-independent manner and has no effect on nAChRs composed of α2/β2, α3/β2, α4/β2, α2/β4, α3/β4, or α4/β4 subunits1,2.
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分子量
- 1924 Da
抗原
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