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Parathyroid Hormone (PTH) (AA 4-13) Peptide

PTH 宿主: 合成
Rockland
产品编号 ABIN6699483
Supplier Product No.: 000-001-m29
发货至: 中国
  • 抗原 See all PTH products
    PTH (Parathyroid Hormone (PTH))
    蛋白结构域
    AA 4-13
    资源
    • 19
    合成
    Supplier Product No.
    000-001-m29
    Supplier
    Rockland
    原理
    Parathyroid hormone (pTH) Rat 4-13 Peptide
    纯度
    Greater than 95% specific peptide.
  • 应用备注

    Other: Control peptide should be used at 1.0 μg per 1.0 μL of antiserum per assay.

    Application_Note: Parathyroid hormone (pTH) Rat 4-13 Control Peptide is suitable for use in ELISA, Western Blot, Dot blot, PCA, and other assays. Control peptide should be used at 1.0 μg per 1.0 μL of antiserum in per assay. Specific conditions for reactivity should be optimized by the end user.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式

    Reconstitution_Buffer: Restore with deionized water (or equivalent)

    Reconstitution_Volume: 1.0 mL

    浓度
    1.0 mg/mL
    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at 2 - 8 ° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilute only prior to immediate use.
    有效期
    12 months
  • 抗原
    PTH (Parathyroid Hormone (PTH))
    物质类
    Hormone
    背景

    Synonyms: Parathyroid hormone, PTH, Parathormone, Parathyrin, control peptide, blocking peptide

    Background: Parathyroid hormone (pTH) is the most important endocrine regulator of Ca2+ and phosphorus concentration in the extracellular fluid. pTH is secreted from cells of the parathyroid glands and acts for the most part via the binding to specific G-protein coupled receptors on the surface of  target cells in bone and kidney, utilizing the second messenger adenylate cyclase to regulate cAMP levels in cells.  Like most other protein hormones, parathyroid hormone is synthesized as a preprohormone and is processed intracellularly.  The mature hormone, 84 amino acids in length, is released from secretory vesicles into the blood.  Biologic effects of large C-terminal parathyroid hormone (PTH) fragments, such as pTH 7-84, are thought to regulate PTH secretion via an autocrine/paracrine regulatory mechanism

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